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It can be said that Surah al-Fatihah's central theme is ‘the clarification of the way to worship Allah Alone’ and the Qur’an as a whole. The Makkan and Madinan revelations revolve around this central theme. This Prayer is for all those who want to study His Message. It is placed at the very beginning to teach the reader that if he sincerely wants to benefit from the Qur'an, he should offer this prayer to the Rabb of the Universe.
Al-Fatiha teaches that the best thing for a man is to pray for "Guidance towards the Right Way" and to study the Qur'an with the mental attitude of a seeker of truth, and to recognize that the Rabb of the Universe is the source of all knowledge. They should, therefore, begin the study of Al-Qur'an with a prayer to Allah for guidance. It is important to know that the real relation between Al-Fatiha and the Qur'an is of a prayer and its answer. Al-Fatiha is the prayer from the devotee and the rest of the Qur'an is the answer from Allah. The devotee prays to Allah to show the "Right Way" and Allah places the whole of the Qur'an before him in answer to his prayer, as if to say: "This is the Guidance that you have asked for".
It can also be said the Qur'an is the tafsir [explanation] of al-Fatihah, where ideas and themes are expounded upon and explained.